Promethazine is metabolized from the liver to a number of inactive metabolites like sulfoxides of promethazine, N-demethylpromethazine together with other glucuronides.
Administration of codeine could be accompanied by histamine release and will be employed with caution in atopic kids.
Get this medication by mouth with or without meals as directed by your medical professional, typically each four to six several hours as necessary. This medication is often taken with food items if tummy upset happens. Drink a lot of fluids once you use this medication unless or else directed by your medical professional.
The dose of the drugs are going to be unique for various clients. Observe your medical professional's orders or perhaps the directions to the label. The following information contains only the common doses of the medicine. When your dose is different, do not adjust it Unless of course your medical doctor informs you to do so.
To aid avoid withdrawal, your health care provider might reduce your dose slowly and gradually. Withdrawal is a lot more most likely When you've got used this medication for some time (quite a lot of weeks) or in higher doses. Explain to your medical doctor or pharmacist right away For those who have withdrawal.
Promethazine: Promethazine is actually a phenothiazine derivative which differs structurally through the antipsychotic phenothiazines with the existence of the branched aspect chain and no ring substitution.
Other Uncomfortable side effects not mentioned may also occur in some clients. Should you recognize some other effects, Look at with your healthcare Skilled.
Codeine is probably the Obviously developing phenanthrene alkaloids of opium derived from your opium poppy; it is classified pharmacologically being a narcotic check here analgesic.
Promethazine and codeine may induce marked drowsiness or might impair the psychological and/or Actual physical talents required for your efficiency of potentially hazardous responsibilities, such as driving a auto or running equipment.
Will not acquire this medication for numerous days just before allergy testing due to the fact test outcomes is usually influenced.
Usually consult your healthcare company to guarantee the information shown on this webpage applies to your personal circumstances.
People should be cautioned to prevent extended Solar publicity and report any involuntary muscle movement.
The concomitant use of Promethazine with Codeine Oral Solution with all cytochrome P450 2D6 inhibitors (e.g., amiodarone, quinidine) could result in an increase in codeine plasma concentrations along with a lower in Lively metabolite morphine plasma concentration which could end in an analgesic efficacy reduction or signs of opioid withdrawal.
Keep at place temperature clear of light-weight and humidity. Usually do not keep in the lavatory. Never freeze. Keep all medicines far from kids and Animals.